α-MAPI |  | | PRODUCT LINE | Signal Transduction | | | | PRODUCT FAMILIES | Proteases Other Products | | | | | Ordering Information | | | Product Numbers | Format | Size | Unit Price | Quantity | | | ALX-260-095-M001 |
|
1 mg | | | | | ALX-260-095-M005 |
|
5 mg | | | | | | |
| | | Product Specification | | |
| FORMULA: | C30H41N7O6 | | | | | |
| MW: | 595.7 | | | | | |
| SOURCE/HOST: | Synthetic. | | | | | |
| PURITY: | ≥95% | | | | | |
| APPEARANCE: | White powder. | | | | | |
| SOLUBILITY: | Soluble in methanol; soluble in water (2mg/ml) after sonification. | | | | | |
| SHIPPING: | AMBIENT | | | | | |
| LONG TERM STORAGE: | -20°C | | | | | | Product Description | Microbial alkaline proteinase inhibitor (α-MAPI) binds strongly to the active site of the HIV protease. |
| | | Product Specific Literature References | Structural elucidation of alpha-MAPI, a novel microbial alkaline proteinase inhibitor, produced by Streptomyces nigrescens: T. Watanabe, et al.; THL 7, 625 (1979)
A high throughput assay for inhibitors of HIV-1 protease. Screening of microbial metabolites: E. Sarubbi, et al.; FEBS Lett. 279, 265 (1991) Abstract
First efficient synthesis of alpha-MAPI: R.J. Broadbridge, et al.; Chem. Commun. 1998, 1449 |
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