α-Melanocyte Stimulating Hormone |  | | SYNONYMS | α-MSH | | | | PRODUCT LINE | Signal Transduction | | | | PRODUCT FAMILIES | Hormones & Hormone Receptors Other Products | | | | | Ordering Information | | | Product Numbers | Format | Size | Unit Price | Quantity | | | LKT-M7528-M001 |
|
1 mg | | | | | | |
| | | Product Specification | | |
| SEQUENCE: | Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 | | | | | |
| FORMULA: | C77H109N21O19S | | | | | |
| MW: | 1664.88 | | | | | |
| CAS NUMBER: | 581-05-5 | | | | | | Product Description | Immunomodulating neuropeptide. Exerts anti-inflammatory action by inhibition of iNOS (NOS II). Regulates protein ubiquitination in T cells. |
| | | Product Specific Literature References | Selective effects of alpha-MSH and MIF-1 on the blood-brain barrier: R. Sankar, et al.; Peptides 2, 345 (1981) Abstract
Biological and immunological characterization of alpha-melanocyte-stimulating hormone (alpha-MSH) in two neuronal systems of the rat brain: S. Jegou, et al.; Brain Res. 260, 91 (1983) Abstract
alpha-MSH exhibits opioid antagonist-like effects in the brainstem of rats: D.A. Carter & S.L. Lightman; Peptides 8, 1173 (1987) Abstract
Alpha-MSH and Parkinson disease: I. Rainero & L. Pinessi; Ital. J. Neurol. Sci. 9, 95 (1988) Abstract
Anti-inflammatory actions of the neuroimmunomodulator alpha-MSH: J.M. Lipton & A. Catania; Immunol. Today 18, 140 (1997), (Review) Abstract
Mechanisms of anti-inflammatory action of the neuroimmunomodulatory peptide alpha-MSH: J.M. Lipton & A. Catania; Ann. N. Y. Acad. Sci. 840, 373 (1998), (Review) Abstract
The neuropeptide alpha-MSH in HIV infection and other disorders in humans: A. Catania, et al.; Ann. N. Y. Acad. Sci. 840, 848 (1998), (Review) Abstract
Alpha-MSH peptides inhibit production of nitric oxide and tumor necrosis factor-alpha by microglial cells activated with beta-amyloid and interferon gamma: D. Galimberti, et al.; BBRC 263, 251 (1999) Abstract
Mechanisms of the antiinflammatory effects of alpha-MSH. Role of transcription factor NF-kappa B and adhesion molecule expression: D.H. Kalden, et al.; Ann. N. Y. Acad. Sci. 885, 254 (1999) Abstract
alpha-MSH inhibits lipopolysaccharide induced nitric oxide production in B16 mouse melanoma cells: M. Tsatmali, et al.; Ann. N. Y. Acad. Sci. 885, 474 (1999) Abstract
Antimicrobial effects of alpha-MSH peptides: M. Cutuli, et al.; J. Leukoc. Biol. 67, 233 (2000) Abstract
The neuroimmunomodulatory peptide alpha-MSH: T. Ichiyama, et al.; Ann. N. Y. Acad. Sci. 917, 221 (2000), (Review) Abstract
The neuropeptide alpha-MSH in host defense: A. Catania, et al.; Ann. N. Y. Acad. Sci. 917, 227 (2000), (Review) Abstract
Neuropeptide regulation of immunity. The immunosuppressive activity of alpha-melanocyte-stimulating hormone (alpha-MSH): A.W. Taylor, et al.; Ann. N. Y. Acad. Sci. 917, 239 (2000) Abstract
The immunomodulating neuropeptide alpha-melanocyte-stimulating hormone (alpha-MSH) suppresses LPS-stimulated TLR4 with IRAK-M in macrophages: A.W. Taylor; J. Neuroimmunol. 162, 43 (2005) Full Text; http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1363363&blobtype=pdf
Alpha-MSH regulates protein ubiquitination in T cells: D.J. Biros, et al.; Cell. Mol. Biol. (Noisy-le-grand) 52, 33 (2006) Abstract |
| | | | | RELATED PRODUCT GROUPS | Nitric Oxide Pathway > Nitric Oxide Synthases [NOS] / Related Products > NOS Inhibitors (NOS Induction & Enzyme Activity) / Peptides | | | | | |
