PRODUCT PROPERTIES |
Alternative Name: | | LFA-3 |
Clone: | | TS2/9 |
Host: | | Mouse |
Isotype: | | IgG1 |
Immunogen: | | Human cytotoxic T cells. |
Species reactivity: | | Human
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Specificity: | | Recognizes both transmembrane and GPI-anchored human CD58 (LFA-3). |
Applications: | | ELISA, Flow Cytometry, IHC, WB, FUNC
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Long Term Storage: | | +4°C |
Background / Technical Information: | | For the Original Manufacturer's Data Sheet please click on the corresponding product number: ANC-210-020 ANC-210-030 ANC-210-040 ANC-210-050 ANC-210-820 |
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Product Literature References
Endothelial cell costimulation of T cell activation through CD58-CD2 interactions involves lipid raft aggregation: J. Mestas & C.C. Hughes; J. Immunol.
167, 4378 (2001),
Abstract;
Full Text
CD18/CD54(+CD102), CD2/CD58 pathway-independent killing of lymphokine-activated killer (LAK) cells against glioblastoma cell lines T98G and U373MG: F. Komatsu and M. Kajiwara; Oncol. Res.
12, 17 (2000),
Abstract;
Cell-specific, activation-dependent regulation of neutrophil CD32A ligand-binding function: S. Nagarajan, et al.; Blood
95, 1069 (2000),
Abstract;
Full Text
T. Kishimoto, et al.; Garland Publishing Inc. - Leukocyte Typing IV 414 (1997),
Interaction between human CD2 and CD58 involves the major beta sheet surface of each of their respective adhesion domains: A.R. Arulanandam, et al.; J. Exp. Med.
180, 1861 (1994),
Abstract;
Biosynthesis and function of LFA-3 in human mutant cells deficient in phosphatidylinositol-anchored proteins: N. Hollander, et al.; J. Immunol.
141, 4283 (1988),
Abstract;
Serologic cross-reactivity of T11 target structure and lymphocyte function-associated antigen 3. Evidence for structural homology of the sheep and human ligands of CD2: G. Tiefenthaler, et al.; J. Immunol.
139, 2696 (1987),
Abstract;