PRODUCT PROPERTIES |
Alternative Name: | | NKR-P1A |
Clone: | | B199.2 |
Host: | | Mouse |
Isotype: | | IgG2b |
Immunogen: | | Activated human NK cells. |
Species reactivity: | | Human
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Specificity: | | Recognizes human dimeric CD161 (NKR-P1A). |
Applications: | | Flow Cytometry
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Long Term Storage: | | +4°C |
Miscellaneous/General: | | Human CD161 is a homodimeric disulfide-linked type II membrane bound glycoprotein found mainly on NK cells. CD161 has been implicated in the regulation of NK cell mediated cytotoxicity. |
Background / Technical Information: | | For the Original Manufacturer's Data Sheet please click on the corresponding product number: ANC-388-020 ANC-388-030 ANC-388-040 ANC-388-050 ANC-388-820 |
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Product Literature References
Differential transcriptional regulation of CD161 and a novel gene, 197/15a, by IL-2, IL-15, and IL-12 in NK and T cells: L. Azzoni, et al.; J. Immunol.
161, 3493 (1998),
Abstract;
T. Kishimoto, et al.; Garland Publishing, Inc. - Leukocyte Typing VI 307 (1997),
Definition of a natural killer NKR-P1A+/CD56-/CD16- functionally immature human NK cell subset that differentiates in vitro in the presence of interleukin 12: I.M. Bennett, et al.; J. Exp. Med.
184, 1845 (1996),
Abstract;