This is a rabbit polyclonal antibody against MYF5. It was validated on Western Blot by Aviva Systems Biology.
|Immunogen:||The immunogen for anti-MYF5 antibody: synthetic 67 directed towards the N terminal of human MYF5|
|Species reactivity:||Human, Mouse, Rat|
|Reconstitution:||Add 50 µl of distilled water. Final anti-MYF5 antibody concentration is 1 mg/ml in PBS buffer.|
|Long Term Storage:||-20°C|
|Miscellaneous/General:||RTKN mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. RTKN may play a novel role in the organization of septin structures.This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.|
|Background / Technical Information:||http://www.uniprot.org/uniprot/Q9BST9||