This is a rabbit polyclonal antibody against TFEC. It was validated on Western Blot by Aviva Systems Biology.
|Immunogen:||The immunogen for anti-TFEC antibody: synthetic 67 directed towards the N terminal of human TFEC|
|Reconstitution:||Add 50 µl of distilled water. Final anti-TFEC antibody concentration is 1 mg/ml in PBS buffer.|
|Long Term Storage:||-20°C|
|Miscellaneous/General:||Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.|
|Background / Technical Information:||http://www.uniprot.org/uniprot/Q9H3R5||