This is a rabbit polyclonal antibody against MIER1. It was validated on Western Blot by Aviva Systems Biology.
| PRODUCT PROPERTIES |
| Appearance: | | Lyophilized powder |
| Host: | | Rabbit |
| Isotype: | | IgG |
| Immunogen: | | The immunogen for anti-MIER1 antibody: synthetic 67 directed towards the middle region of human MIER1 |
| Species reactivity: | | Human
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| Applications: | | WB
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| Reconstitution: | | Add 100 µl of distilled water. Final anti-MIER1 antibody concentration is 1 mg/ml in PBS buffer. |
| Long Term Storage: | | -20°C |
| Miscellaneous/General: | | The protein is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. |
| Background / Technical Information: | | http://www.uniprot.org/uniprot/O14763 |
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United States
