This is a rabbit polyclonal antibody against LAS1L. It was validated on Western Blot by Aviva Systems Biology.
| PRODUCT PROPERTIES |
| Appearance: | | Lyophilized powder |
| Host: | | Rabbit |
| Isotype: | | IgG |
| Immunogen: | | The immunogen for anti-LAS1L antibody: synthetic 67 directed towards the C terminal of human LAS1L |
| Species reactivity: | | Human
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| Applications: | | WB
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| Reconstitution: | | Add 100 µl of distilled water. Final anti-LAS1L antibody concentration is 1 mg/ml in PBS buffer. |
| Long Term Storage: | | -20°C |
| Miscellaneous/General: | | This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. |
| Background / Technical Information: | | http://www.uniprot.org/uniprot/P08684 |
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United States
