This is a rabbit polyclonal antibody against HOXC9. It was validated on Western Blot by Aviva Systems Biology.
| PRODUCT PROPERTIES |
| Appearance: | | Lyophilized powder |
| Host: | | Rabbit |
| Immunogen: | | The immunogen for anti-HOXC9 antibody: synthetic 67 directed towards the N terminal of human HOXC9 |
| Species reactivity: | | Human
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| Applications: | | WB
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| Reconstitution: | | Add 100 µl of distilled water. Final anti-HOXC9 antibody concentration is 1 mg/ml in PBS buffer. |
| Long Term Storage: | | -20°C |
| Miscellaneous/General: | | ERVWE1 or syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene.Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The product of this gene, syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Background / Technical Information: | | http://www.uniprot.org/uniprot/Q9UQF0 |
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United States
