This is a rabbit polyclonal antibody against ATF4. It was validated on Western Blot by Aviva Systems Biology.
|Immunogen:||The immunogen for anti-ATF4 antibody: synthetic 67 directed towards the N terminal of mouse ATF4|
|Species reactivity:||Human, Mouse, Rat|
Bovine, Chicken, Dog, Porcine, Xenopus, Zebrafish
|Reconstitution:||Add 50 µl of distilled water. Final anti-ATF4 antibody concentration is 1 mg/ml in PBS buffer.|
|Long Term Storage:||-20°C|
|Miscellaneous/General:||The protein encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.||