This is a rabbit polyclonal antibody against RP11-78J21.1. It was validated on Western Blot and immunohistochemistry by Aviva Systems Biology.
| PRODUCT PROPERTIES |
| Appearance: | | Lyophilized powder |
| Host: | | Rabbit |
| Isotype: | | IgG |
| Immunogen: | | The immunogen for anti-RP11-78J21.1 antibody: synthetic 67 directed towards the N terminal of human RP11-78J21.1 |
| Species reactivity: | | Human, Mouse, Rat
Bovine, Xenopus
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| Applications: | | IHC, WB
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| Reconstitution: | | Add 100 µl of distilled water. Final anti-RP11-78J21.1 antibody concentration is 1 mg/ml in PBS buffer. |
| Long Term Storage: | | -20°C |
| Miscellaneous/General: | | GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP; MIM 112260) and bone matrix protein (MGP; MIM 154870).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Background / Technical Information: | | http://www.uniprot.org/uniprot/P38435 |
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United States
