This is a rabbit polyclonal antibody against HNRPH3. It was validated on Western Blot and immunohistochemistry by Aviva Systems Biology.
|Immunogen:||The immunogen for anti-HNRPH3 antibody: synthetic 67 directed towards the N terminal of human HNRPH3|
|Reconstitution:||Add 100 µl of distilled water. Final anti-HNRPH3 antibody concentration is 1 mg/ml in PBS buffer.|
|Long Term Storage:||-20°C|
|Miscellaneous/General:||SIGLEC7 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. In the immune response, it may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. SIGLEC7 mediates inhibition of natural killer cells cytotoxicity. It may also play a role in hemopoiesis. SIGLEC7 inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).|
|Background / Technical Information:||http://www.uniprot.org/uniprot/Q9Y286||