This is a rabbit polyclonal antibody against STS. It was validated on Western Blot by Aviva Systems Biology.
|Immunogen:||The immunogen for anti-STS antibody: synthetic 67 directed towards the C terminal of human STS|
|Species reactivity:||Human, Mouse, Rat|
|Reconstitution:||Add 100 µl of distilled water. Final anti-STS antibody concentration is 1 mg/ml in PBS buffer.|
|Long Term Storage:||-20°C|
|Miscellaneous/General:||DISP1 functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal.The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo.|
|Background / Technical Information:||http://www.uniprot.org/uniprot/Q96F81||