This is a rabbit polyclonal antibody against COBLL1. It was validated on Western Blot and immunohistochemistry by Aviva Systems Biology.
| PRODUCT PROPERTIES |
| Appearance: | | Lyophilized powder |
| Host: | | Rabbit |
| Immunogen: | | The immunogen for anti-COBLL1 antibody: synthetic 67 directed towards the N terminal of human COBLL1 |
| Species reactivity: | | Human
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| Applications: | | IHC, WB
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| Reconstitution: | | Add 50 µl of distilled water. Final anti-COBLL1 antibody concentration is 1 mg/ml in PBS buffer. |
| Long Term Storage: | | -20°C |
| Miscellaneous/General: | | The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. |
| Background / Technical Information: | | http://www.uniprot.org/uniprot/P21217 |
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United States
