Site selective cAMP analog with preference for site B of R I of cAMP-dependent protein kinase. In combination with 8-piperidino-cAMP (Prod. No. BLG-P002
) which selects site A of R I and site B of R II selective synergistic activation of protein kinase A type I can be obtained. Increased membrane permeability compared to 8-ABA-cAMP . Also suitable as a ligand in affinity chromatography (8-AHA-cAMP-Agarose; Prod. No. BLG-A028
) or surface plasmon resonance chip technology  and for modification with fluorophores.
|Purity:||>98% by HPLC|
|Long Term Storage:||-20°C|
|Background / Technical Information:||For the Original Manufacturer's Data Sheet please click here.|
Our product description may differ slightly from the Original Manufacturer's Data Sheet.
|Manufacturer:||manufactured by Biolog Life Science Institute|
Product Literature References
Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding
: F.W. Herberg, et al.; J. Mol. Biol. 298
, 329 (2000), Abstract
Cyclic AMP-dependent protein kinase type I mediates the inhibitory effects of 3',5'-cyclic adenosine monophosphate on cell replication in human T lymphocytes
: B.S. Skalhegg, et al.; J. Biol. Chem. 267
, 15707 (1992), Abstract
; Full Text