Potent and lipophilic activator of protein kinase A, type I & II. Ten times more active compared to cyclic AMP but rapidly degraded by cyclic nucleotide-dependent phosphodiesterases. There is also a PDE-resistant form of this compound (Sp-5,6-DCl-cBIMPS Prod. No.
BLG-D014).
| PRODUCT PROPERTIES |
| Alternative Name: | | 5,6-Dichloro-1-β-D-ribofuranosyl benzimidazole-3',5'-cyclic monophosphate . sodium salt, cDRBMP |
| Formula: | | C12H10Cl2N2O6P . Na |
| MW: | | 403.1 |
| CAS: | | 129693-10-3 |
| Quantity: | | 10µmol=~4mg |
| Purity: | | > 98% HPLC |
| Long Term Storage: | | -20°C |
| Background / Technical Information: | | For the Original Manufacturer's data sheet please click here. |
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Product Literature References
Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates: W.R. Dostmann, et al.; J. Biol. Chem.
265, 10484 (1990),
Abstract;
Full Text
United States
