In 8-[φ-575]-2’-O-Me-cAMP the relatively small Pharos 575 dye is connected to position 8 of the heterocyclic nucleobase of cyclic AMP (cAMP) via a spacer. In addition, the ribose 2’-hydroxy group has been methylated.
8-[φ-575]-2’-O-Me-cAMP is a fluorescent analogue of cAMP with λexc 577 nm and λem 605 nm. The fluorophore can be excited e.g. by a Kr/Ar laser. Due to its high lipophilicity/membrane permeability and bright red fluorescence, 8-[φ-575]-2’-O-Me-cAMP is especially suitable for studies with intact cells.
|Solubility:||Has limited solubility in water, but is better soluble in methanol.|
|Long Term Storage:||-20°C|
|Miscellaneous/General:||Legal information: The Reagent is subject to patent application n° EP 02077219.0 and foreign equivalents. The Reagent and any improvements are owned and licensed by The UMCU/ UMCU Holding Pharmaceuticals. The Reagent is sold under limited, non transferable and non exclusive licence from The UMCU/ UMCU Holding for research purposes only, to the exclusion of any commercial use, transfer or otherwise sale of this Reagent or its components or derivatives to a third party. Use or sale of Reagent for any commercial purposes requires a commercial license from The UMCU - Universiteitsweg 100, Utrecht, The Netherlands / UMCU Holding - Yalelaan 40, Utrecht, The Netherlands.|
|Background / Technical Information:||For the Original Manufacturer's Data Sheet please click here.|
Our product description may differ slightly from the Original Manufacturer's Data Sheet.
|Manufacturer:||manufactured by Biolog Life Science Institute|