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Cyclopamine

A hedgehog signaling inhibitor
 
BV-1578-5 5 mg 226.00 USD
 
Cyclopamine blocks activation of the Hedgehog response pathway associated with mutations that either activate the proto-oncogene Smoothened (Smo) or inactivate the tumour suppressor Patched (Ptch) both of which encode multipass transmembrane proteins.  Furthermore, it has been demonstrated that the inhibitory effect of cyclopamine results from its direct binding to the Smo heptahelical protein bundle
PRODUCT PROPERTIES
Formula:C27H41NO2
MW:411.62
CAS:4449-51-8
Purity:≥99%
Appearance:Off-white solid
Solubility:DMSO (4 mg/ml) and EtOH (5 mg/ml)
Long Term Storage:-20°C
Background / Technical Information:For the Original Manufacturer's data sheet please click here.

TECHNICAL DOCUMENTS

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CATALOG SECTION

Hedgehog [Hh] Signaling Pathway
Hedgehog [Hh] Signaling Pathway
Hedgehog [Hh] Signaling Pathway
Hedgehog [Hh] Signaling Pathway
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