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Imatinib Mesylate

A bcr-abl tyrosine kinase inhibitor
 
BV-1625-5000 5 g Inquire for pricing
 
BV-1625-100 100 mg 108.00 USD
 
BV-1625-1000 1 g 391.00 USD
 
An inhibitor of the bcr-abl tyrosine kinase. It acts by binding to the ATP binding site of bcr-abl. Imatinib also stimulates the entry of the bcr-abl tyrosine kinase into the nucleus, where it cannot perform its anti-apoptopic functions. It inhibits EOL-1 cell viability (IC50 = 0.5 nM), phosphorylation of a fusion protein (IC50 = 30 nM), and viability of BaF3 cells expressing Rhe-PDGFRα in the absence of IL-3 (IC50 = 0.17 nM).
PRODUCT PROPERTIES
Formula:C29H31N7O . CH4SO3
MW:589.71
CAS:220127-57-1
Purity:≥99% by HPLC
Appearance:White to off-white solid
Solubility:DMSO (100 mg/ml)
Long Term Storage:-20°C
Background / Technical Information:For the Original Manufacturer's data sheet please click here.

TECHNICAL DOCUMENTS

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