| PRODUCT PROPERTIES |
| Alternative Name: | | CASP-11, ICEB, ICH-3 |
| Host: | | Rabbit |
| Isotype: | | IgG |
| Immunogen: | | Synthetic peptide surrounding amino acid 257 of rat caspase-11 |
| Species reactivity: | | Mouse, Rat
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| Applications: | | WB
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| Application Notes: | | The antibody detects procaspase-11 (45 kDa), a partially cleaved fragment (30 kDa) and fully cleaved fragment (20 kDa). A 58 kDa unknown identity band was also detected in 3T3 cells. |
| Purity Detail: | | Affinity purified |
| Concentration: | | 0.2 mg/ml |
| Appearance: | | Colorless liquid |
| Formulation: | | Liquid. In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
| Handling: | | Avoid freeze/thaw cycles. |
| Short Term Storage: | | -20°C |
| Long Term Storage: | | -20°C |
| Miscellaneous/General: | | Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-11 is also synthesized as inactive pro-enzyme that are processed in cells undergoing apoptosis or inflammation. The processed form of caspase-11 consists of large and small subunits which associate to form an active enzyme. |
| Background / Technical Information: | | For the Original Manufacturer's data sheet please click here. |
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United States
