PRODUCT PROPERTIES |
Alternative Name: | | CYCS, CYC |
Clone: | | 7H8.2C12 |
Host: | | Mouse |
Isotype: | | IgG2b |
Immunogen: | | Pigeon cytochrome c |
Species reactivity: | | Human, Mouse, Rat
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Applications: | | WB
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Application Notes: | | The antibody detects a 12.0 kDa protein corresponding to the apparent molecular weight of cytochrome c. |
Purity Detail: | | Affinity purified |
Concentration: | | 0.2 mg/ml |
Appearance: | | Colorless liquid |
Formulation: | | Liquid. In PBS containing 50% glycerol, 0.5 % BSA and 0.01% Thimerosal and 50% glycerol |
Long Term Storage: | | -20°C |
Miscellaneous/General: | | Cytochrome c (m.w. 12,500) is an electron transport protein from mitochondria. It is released from mitochondria to cytoplasm during the early stages of apoptosis, prior to caspase activation, DNA fragmentation, and loss of membrane potential. The cytoplasmic cytochrome c is associated with Apaf-1 and caspase-9 to activate caspase-3 and other caspases. |
Background / Technical Information: | | For the Original Manufacturer's data sheet please click here. |
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