| PRODUCT PROPERTIES |
| Alternative Name: | | MAPK1, MAPK2 |
| Appearance: | | Colorless liquid |
| Host: | | Rabbit |
| Isotype: | | Rabbit IgG |
| Immunogen: | | Synthetic peptide from human Erk2 |
| Species reactivity: | | Human, Mouse, Rat
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| Applications: | | IHC, WB
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| Purity Detail: | | Affinity Purified Antibody |
| Concentration: | | 0.5 mg/ml |
| Formulation: | | 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal. |
| Long Term Storage: | | -20°C |
| Miscellaneous/General: | | Both p44 and p42 MAP kinases (Erk1 and Erk2) function in a protein kinase cascade that plays a critical role in the regulation of cell growth and differentiation. Activation of MAP kinases occurs through phosphorylation of threonine and tyrosine (202 and 204 of human MAP kinase [Erk1] or 183 and 185 of rat Erk2) at the sequence T*EY* by a single upstream MAP kinase kinase (MEK). Both kinases are known to weakly autophosphorylate on tyrosine. |
| Background / Technical Information: | | For the Original Manufacturer's data sheet please click here. |
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United States
