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TFAM polyclonal antibody

 
BV-3885-30T 30 µg 98.00 USD
 
BV-3885-100 100 µg 270.00 USD
 
PRODUCT PROPERTIES
Alternative Name:Transcription factor A (mitochondrial), mtTFA, Transcription factor 6, TCF-6
Host:Rabbit
Isotype:IgG
Immunogen:Synthetic peptide corresponding to residues surrounding amino acid 225 of rat TFAM
UniProt ID:Q91ZW1
Species reactivity:Rat
Applications:WB
Application Notes:The antibody recognizes 27 kDa band from rat kidney tissue lysate.
Purity Detail:Affinity purified
Concentration:0.5 mg/ml
Appearance:Colorless liquid
Formulation:Liquid. In phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Long Term Storage:-20°C
Miscellaneous/General:Transcription factor A mitochondria (TFAM) is an important activator of mitochondrial DNA transcription and replication. Studies in mice have shown that TFAM is required to regulate the mitochondrial genome copy number and is important for embryonic development. TFAM has been associated with mitochondrial disorder which includes ocular myopathy and muscular wasting in humans. Kearns-Sayre syndrome was shown in mouse model when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
Background / Technical Information:For the Original Manufacturer's data sheet please click here.

TECHNICAL DOCUMENTS

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