| PRODUCT PROPERTIES |
| Alternative Name: | | Stromal cell-derived factor 1, DF-1, C-X-C motif chemokine 12, CXCL12, Pre-B cell growth-stimulating factor, PBSF |
| Host: | | Rabbit |
| Isotype: | | Rabbit IgG |
| Immunogen: | | E. coli-expressed mouse SDF-1β |
| Species reactivity: | | Mouse, Rat
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| Applications: | | WB
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| Purity Detail: | | Affinity Purified Antibody |
| Concentration: | | 0.5 mg/ml |
| Formulation: | | 100 µg (0.5 mg/ml) Protein A purified rabbit anti-SDF-1β polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
| Long Term Storage: | | -20°C |
| Miscellaneous/General: | | SDF-1β (stromal cell-derived factor-β), also known as pre-B-cell growth-stimulating factor (PBSF), is a 74-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry. |
| Background / Technical Information: | | For the Original Manufacturer's data sheet please click here. |
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United States
