| PRODUCT PROPERTIES |
| Alternative Name: | | Stromal cell-derived factor 1, DF-1, C-X-C motif chemokine 12, CXCL12, Pre-B cell growth-stimulating factor, PBSF |
| Host: | | Rabbit |
| Isotype: | | IgG |
| Immunogen: | | E. coli-expressed mouse SDF-1β |
| UniProt ID: | | P40224 |
| Species reactivity: | | Mouse, Rat
|
| Applications: | | IHC, IP, WB
|
| Purity Detail: | | Affinity purified |
| Concentration: | | 0.5 mg/ml |
| Appearance: | | Colorless liquid |
| Formulation: | | Liquid. In PBS pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% Proclin. |
| Long Term Storage: | | -20°C |
| Miscellaneous/General: | | SDF-1β (stromal cell-derived factor-β), also known as pre-B-cell growth-stimulating factor (PBSF), is a 74-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry. |
| Background / Technical Information: | | For the Original Manufacturer's data sheet please click here. |
|
|
|
United States
