| PRODUCT PROPERTIES |
| Alternative Name: | | T cell receptor beta |
| Host: | | Rabbit |
| Isotype: | | Rabbit IgG |
| Immunogen: | | Synthetic peptide surrounding amino acid 114 of human TCR-β |
| Species reactivity: | | Human, Mouse, Rat
|
| Applications: | | WB
|
| Application Notes: | | Based on researcher’s feedback, the antibody can also be used in immunoprecipitation (10-20 µg/ml); and (15-25 µg/ml). The antibody recognizes 34 kDa TCR β of human, mouse, and rat origins. MOLT-4 cell lysate can be used as a positive control. |
| Purity Detail: | | Affinity Purified Antibody |
| Concentration: | | 0.2 mg/ml |
| Formulation: | | 100 µg (0.2 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal. |
| Long Term Storage: | | -20°C |
| Miscellaneous/General: | | TCR (T cell antigen receptor) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR is a heterodimer composed of either α and β or γ and δ chains. The vast majority of circulating T cells (95%) express the α/β heterodimer while roughly 2-5% express the γ/δ heterodimer. CD3 chains and the CD4 or CD8 coreceptors are also required for efficient signal transduction through the TCR. |
| Background / Technical Information: | | For the Original Manufacturer's data sheet please click here. |
|
|
|
United States
