Belizatinib (TSR-011) is a potent inhibitor of both the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) and the tropomyosin-related kinases (TRK) TRKA, TRKB, and TRKC, with potential antineoplastic activity. The inhibition leads to disruption of ALK- and TRK-mediated signaling and impedes tumor cell growth in ALK/TRK-overexpressing tumor cells.
PRODUCT PROPERTIES |
Formula: | | C33H44FN5O3 |
MW: | | 577.75 |
CAS: | | 1357920-84-3 |
Purity: | | ≥98% by HPLC |
Appearance: | | Crystalline solid |
Solubility: | | DMSO |
Long Term Storage: | | -20°C |
Background / Technical Information: | | For the Original Manufacturer's data sheet please click here. |
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