Piperine is the primary pungent alkaloid isolated from the fruit of black peppercorns. It displays a variety of therapeutic activities such as anti-oxidant, anti-inflammatory, immunomodulatory, anti-asthmatic, anti-convulsant, anti-mutagenic, antimycobacterial, anti-amoebic, and anti-cancer activities. Piperine affects cytochrome P450 (CYP) isoforms, inhibiting CYP3A species (Ki ~ 5 µM) and increasing expression of CYP1A and CYP2B in liver. It also has a biphasic effect on P-glycoprotein activity.
PRODUCT PROPERTIES |
Formula: | | C17H19NO3 |
MW: | | 285.354 |
CAS: | | 94-62-2 |
Purity: | | ≥98% by HPLC |
Appearance: | | White to off-white solid. |
Solubility: | | DMSO (~10 mg/ml) |
Long Term Storage: | | -20°C |
Background / Technical Information: | | For the Original Manufacturer's data sheet please click here. |
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