C-DIM 12 activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth. Nurr1 is a suppressor of NF-kB-related neuroinflammatory genes in microglia and astrocytes and C-DIM 12 suppresses inflammatory signaling in these cells. Displays neuroprotective activity in a mouse model of progressive neurodegeneration with a strong neuroinflammatory component (50 mg/Kg, oral).
PRODUCT PROPERTIES |
Formula: | | C23H17ClN2 |
MW: | | 356.9 |
CAS: | | 178946-89-9 |
Purity: | | ≥98% by TLC |
Appearance: | | Orange powder. |
Solubility: | | DMSO (35 mg/ml) or EtOH (35 mg/ml) |
Long Term Storage: | | -20°C |
Background / Technical Information: | | For the Original Manufacturer's data sheet please click here. |
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