Fumarate (HO2CCH=CHCO2H-) is an intermediate in the Krebs cycle used by cells to metabolize food to form ATP. In the mammalian liver, fumarate is also a product of the urea cycle where its release in the cytosol leads to its conversion into malate and subsequently oxaloacetate while generating NADH in the cytosol. The human skin naturally produces fumaric acid when exposed to sunlight. In fact, fumaric acid esters have been used to treat psoriasis, possibly due to an impaired production of fumaric acid in the skin.
|Handling:||Protect from light.|
|Long Term Storage:||-20°C|
|Background / Technical Information:||For the Original Manufacturer's Data Sheet please click here.|
Our product description may differ slightly from the Original Manufacturer's Data Sheet.