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Aconitine

Toxin found in Aconitum; voltage-gated Na+ channel modulator.
 
LKT-A0958-M010 10 mg 62.00 USD
 
LKT-A0958-M025 25 mg 108.00 USD
 
LKT-A0958-M100 100 mg 339.00 USD
 
A diterpene alkaloid isolated from Aconiti carmichaeli. Inducer of cardiac arrhythmias. It binds to neurotoxin binding site 2 of the α-subunit of the Na+ channel protein.
PRODUCT PROPERTIES
Alternative Name:20-ethyl-3α,13,15α-trihydroxy-1α,6α,16β-trimethoxy-4-(methoxymethyl)aconitane-8,14α-diyl 8-acetate 14-benzoate, Acetylbenzoylaconine
Formula:C34H47NO11
MW:645.74
CAS:302-27-2
MI:13: 120
Purity:≥88%
Solubility:Soluble in water (0.3mg/mL) or ethanol (35mg/mL).
Long Term Storage:+4°C
Formula:
lkt-a0958

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CATALOG SECTION

Alkaloids
Neurotoxins
Neurotoxins
Na+ Channels
Na+ Channels

Product Literature References

The effects of Aconitum alkaloids on the central nervous system: A. Ameri; Prog. Neurobiol. 56, 211 (1998), Abstract;
Involvement of Central adrenergic mechanisms in the induction of cardiac arrhythmias by aconitine nitrate administered intraventricularly: B.V. Telang and J.N. Ng'ang'a; Indian J. Physiol. Pharmacol. 19, 1 (1975), Abstract;
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