A diterpene alkaloid isolated from Aconiti carmichaeli. Inducer of cardiac arrhythmias. It binds to neurotoxin binding site 2 of the α-subunit of the Na+ channel protein.
PRODUCT PROPERTIES |
Alternative Name: | | 20-ethyl-3α,13,15α-trihydroxy-1α,6α,16β-trimethoxy-4-(methoxymethyl)aconitane-8,14α-diyl 8-acetate 14-benzoate, Acetylbenzoylaconine |
Formula: | | C34H47NO11 |
MW: | | 645.74 |
CAS: | | 302-27-2 |
MI: | | 13: 120 |
Purity: | | ≥88% |
Solubility: | | Soluble in water (0.3mg/mL) or ethanol (35mg/mL). |
Long Term Storage: | | +4°C |
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Product Literature References
The effects of Aconitum alkaloids on the central nervous system: A. Ameri; Prog. Neurobiol.
56, 211 (1998),
Abstract;
Involvement of Central adrenergic mechanisms in the induction of cardiac arrhythmias by aconitine nitrate administered intraventricularly: B.V. Telang and J.N. Ng'ang'a; Indian J. Physiol. Pharmacol.
19, 1 (1975),
Abstract;