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Catharanthine . sulfate

Alkaloid found in Catharanthus, precursor in synthesis of vinca alkaloids; voltage-gated Ca2+ channel blocker.
 
LKT-C0377-M005 5 mg 44.00 USD
 
LKT-C0377-M025 25 mg 83.00 USD
 
LKT-C0377-M100 100 mg 138.00 USD
 
LKT-C0377-M500 500 mg 248.00 USD
 
It is one of the many alkaloids present in Catharanthus roseus.  Can be used as a starting material for the synthesis of the anti-tumor drugs, vinblastine and vincristine.  It is less active as an inhibitor of tubulin self-assembly into microtubules than the latter two compounds.
PRODUCT PROPERTIES
Formula:C21H24N2O2 . H2SO4
MW:434.51
MI:13: 1914
Purity:≥98%
Long Term Storage:+4°C
Formula:
lkt-c0377

TECHNICAL DOCUMENTS

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CATALOG SECTION

Natural Products - Antitumor Reagen...
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Microtubule Modulators
Microtubule Modulators
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Natural Products for Cytoskeletal R...
Alkaloids

Product Literature References

Symmetry C18 column: a better choice for the analysis of indole alkaloids of Catharanthus roseus  : G.C. Uniyal, et al. ; Phytochem. Anal. 12, 206 (2001), Abstract;
Mechanism of interaction of vinca alkaloids with tubulin: catharanthine and vindoline  : V. Prakash and S.N. Timasheff ; Biochemistry 30, 873 (1991), Abstract;
Photochemical one-pot synthesis of vinblastine and vincristin  : S. Pennanen and A. Huhtikangas ; Photochem. Photobiol. 51, 515 (1990), Abstract;
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