Catharanthine . sulfate

Alkaloid found in Catharanthus, precursor in synthesis of vinca alkaloids; voltage-gated Ca2+ channel blocker.



LKT-C0377-M005	5 mg	75.00 USD

LKT-C0377-M025	25 mg	141.00 USD

LKT-C0377-M100	100 mg	405.00 USD

LKT-C0377-M500	500 mg	1,132.00 USD

It is one of the many alkaloids present in Catharanthus roseus. Can be used as a starting material for the synthesis of the anti-tumor drugs, vinblastine and vincristine. It is less active as an inhibitor of tubulin self-assembly into microtubules than the latter two compounds.

PRODUCT PROPERTIES
Formula:		C₂₁H₂₄N₂O₂ . H₂SO₄
MW:		434.51
MI:		13: 1914
Purity:		≥98%
Long Term Storage:		+4°C

Formula:

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Product Literature References

Symmetry C18 column: a better choice for the analysis of indole alkaloids of Catharanthus roseus : G.C. Uniyal, et al. ; Phytochem. Anal. 12, 206 (2001), Abstract;

Mechanism of interaction of vinca alkaloids with tubulin: catharanthine and vindoline : V. Prakash and S.N. Timasheff ; Biochemistry 30, 873 (1991), Abstract;

Photochemical one-pot synthesis of vinblastine and vincristin : S. Pennanen and A. Huhtikangas ; Photochem. Photobiol. 51, 515 (1990), Abstract;

Catharanthine . sulfate

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