It is one of the many alkaloids present in Catharanthus roseus. Can be used as a starting material for the synthesis of the anti-tumor drugs, vinblastine and vincristine. It is less active as an inhibitor of tubulin self-assembly into microtubules than the latter two compounds.
PRODUCT PROPERTIES |
Formula: | | C21H24N2O2 .C4H6O6 |
MW: | | 486.52 |
MI: | | 13: 1914 |
Purity: | | ≥97% |
Solubility: | | Soluble in ethanol. |
Long Term Storage: | | +4°C |
Handling: | | Very hygroscopic. |
|
|
|
Product Literature References
Symmetry C18 column: a better choice for the analysis of indole alkaloids of Catharanthus roseus : G.C. Uniyal, et al. ; Phytochem. Anal.
12, 206 (2001),
Abstract;
Mechanism of interaction of vinca alkaloids with tubulin: catharanthine and vindoline : V. Prakash and S.N. Timasheff ; Biochemistry
30, 873 (1991),
Abstract;
Photochemical one-pot synthesis of vinblastine and vincristin : S. Pennanen and A. Huhtikangas ; Photochem. Photobiol.
51, 515 (1990),
Abstract;