A uroprotective agent used in combination with cancer chemotherapeutic drugs to decrease urotoxicity. It was found to have antitumor activity against several cell lines. In addition, it is used as an antimucolytic agent.
PRODUCT PROPERTIES |
Alternative Name: | | 2-Mercaptoethanesulfonic acid sodium salt, MESNA |
Formula: | | C2H5O3S2 . Na |
MW: | | 164.18 |
CAS: | | 19767-45-4 |
MI: | | 13: 5936 |
Purity: | | ≥98% |
Solubility: | | Soluble in water. Slightly soluble in alcohol. Practically insoluble in cyclohexane. |
Long Term Storage: | | Ambient |
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Product Literature References
Antitumor activity of 2-mercaptoethanesulfonate (mesna) in vitro: H. Blomgren, et al.; Methods Find. Exp. Clin. Pharmacol.
12, 691 (1990),
Abstract;
Clinical studies on the mucolytic effect of mesna: M. Tekeres, et al.; Clin. Ther.
4, 56 (1981),
Abstract;
The development of mesna for the inhibition of urotoxic side effects of cyclophosphamide, ifosfamide, and other oxazaphosphorine cytostatics: N. Brock; Recent Results Cancer Res.
74, 270 (1980),
Abstract;