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Vascular Endothelial Growth Factor Receptor 2 (human):Fc (human), Soluble (recombinant)



RLT-SFC-007-C010	10 µg		83.00 USD

PRODUCT PROPERTIES
Alternative Name:		VEGFR-2 (human):Fc (human), Soluble (recombinant), KDR (human):Fc (human), Soluble (recombinant), CD309 (human):Fc (human), Soluble (recombinant)
MW:		~160kDa (monomer).
Source:		Disulfide-linked glycosylated homodimer produced in insect cells. Recombinant human soluble VEGFR-2 (aa 1-757) fused to the Fc part of human IgG1.
EC:		2.7.1.112
Formulation:		Lyophilized from PBS, pH 7.4.
Purity:		≥90% (SDS-PAGE)
Endotoxin Content:		≤1.2EU/µg protein.
Biological Activity:		Inhibits the VEGF-dependent proliferation of human umbilical vein endothelial cells (ED₅₀=10-30ng/ml).
Solubility:		Soluble in water and most aqueous buffers.
Reconstitution:		Reconstitute with PBS or medium (>50µg/ml).
Long Term Storage:		-20°C
Handling:		After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Background / Technical Information:		For the Original Manufacturer’s Data Sheet please click here. Our product description may differ slightly from the Original Manufacturer’s Data Sheet. Swiss-Prot link P35968: VEGFR-2 (human) (precursor) AfCS Signalling Gateway link A000946: VEGFR-2 (mouse)

TECHNICAL DOCUMENTS Print as PDF	RELATED PRODUCTS No related products available
PRODUCT SUPPORT Technical Service Bulk Quantity Quote Customer Service	CATALOG SECTION Vascular Endothelial Growth Factors... Vascular Endothelial Growth Factors... Vascular Endothelial Growth Factors... VEGF Receptors VEGF Receptors VEGF Receptors

Product Literature References

Differential binding characteristics and cellular inhibition by soluble VEGF receptors 1 and 2: W. Roeckl, et al.; Exp. Cell Res. 241, 161 (1998), Abstract;