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Tie-2 (human):Fc (human), Soluble (recombinant)

 
RLT-SFC-013 20 µg 110.00 USD
 
PRODUCT PROPERTIES
Alternative Name:Tek (human):Fc (human), Soluble (recombinant), CD202b (human):Fc (human), Soluble (recombinant)
MW:~250kDa.
Source:Disulfide-linked glycosylated homodimer produced in insect cells. Recombinant human soluble Tie-2 is fused to the Fc portion of human IgG1.
EC:2.7.1.112
Formulation:Lyophilized from PBS.
Purity:≥90% (SDS-PAGE)
Endotoxin Content:≤1.2EU/µg protein.
Biological Activity:Binds recombinant human Ang-2 (angiopoietin-2).
Solubility:Soluble in water and most aqueous buffers.
Reconstitution:Reconstitute with PBS or medium (>50µg/ml).
Long Term Storage:-20°C
Handling:After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Background / Technical Information:For the Original Manufacturer’s Data Sheet please click here.
Our product description may differ slightly from the Original Manufacturer’s Data Sheet.

TECHNICAL DOCUMENTS

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CATALOG SECTION

Angiopoietins & Tie Receptors

Product Literature References

Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development: N.W. Gale & G.D. Yancopoulos; Genes Dev. 13, 1055 (1999), Abstract; Full Text
Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system: T.N. Sato, et al.; PNAS 90, 9355 (1993), Abstract; Full Text
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