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 ALX-151-013[ALEXIS] Revised 01-Feb-09  

Apamin

PRODUCT LINE   

Signal Transduction

PRODUCT FAMILIES   

K+ Channel Blockers & Inhibitors

Ordering Information
 Product NumbersFormatSizeUnit PriceQuantity
 ALX-151-013-MC05 0.5 mg  
Product Specification
SEQUENCE:   H-Cys-Asn-Cys-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys-Ala-Arg-Arg-Cys-Gln-Gln-His-NH2
(Disulfide bonds between Cys1-Cys11and Cys3-Cys15)
 
FORMULA:   C131H131N31O24S4
 
MW:   2027.3
 
CAS NUMBER:   24345-16-2
 
MERCK INDEX:   14: 725
 
RTECS:   CD6899900
 
SOURCE/HOST:   Synthetic.
 
PURITY:   ≥97% (HPLC)
 
APPEARANCE:   Lyophilized.
 
SOLUBILITY:   Soluble in 0.05M acetic acid; slightly soluble in water.
 
SHIPPING:   AMBIENT
 
LONG TERM STORAGE:   -20°C
Product Description

Originally isolated from Apis mellifera. A small conductance Ca2+-activated K+ channel blocker.

Product Specific Literature References
Toxins in the characterization of potassium channels: N.A. Castle, et al.; TINS 12, 59 (1989), (Review) Abstract
Potassium channel toxins: P.N. Strong; Pharmacol. Ther. 46, 137 (1990) Abstract
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Peptides