Bone Metabolism



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 ALX-460-032[ALEXIS] Revised 18-Dec-07  

Calcitriol

SYNONYMS   

Vitamin D3, 1α,25-Dihydroxy-
1α,25-Dihydroxyvitamin D3
1,25(OH)2D3
1α,25-Dihydroxycholecalciferol

PRODUCT LINE   

Bone Metabolism

PRODUCT FAMILIES   

Vitamin D3 & Vitamin D3 Receptor / Related Products

Ordering Information
 Product NumbersFormatSizeUnit PriceQuantity
 ALX-460-032-C100 100 µg  
 ALX-460-032-M001 1 mg  
Product Specification
FORMULA:   C27H44O3
 
MW:   416.7
 
CAS NUMBER:   32222-06-3
 
MERCK INDEX:   14: 1644
 
RTECS:   FZ4645000
 
PURITY:   ≥97%
 
APPEARANCE:   White to off-white solid.
 
SOLUBILITY:   Slightly soluble in methanol, 100% ethanol, ethyl acetate or tetrahydrofuran. 
 
SHIPPING:   SHIPPED ON BLUE ICE
 
LONG TERM STORAGE:   -20°C
 
HANDLING:   Protect from light.
 
HAZARD:   VERY TOXIC. MAY BE TERATOGENIC.

Product Description

Osteotropic hormone that up-regulates RANKL level and down-regulates OPG level. Biologically active form of vitamin D3 in intestinal calcium transport and bone calcium resorption.

Product Specific Literature References
A rapidly acting metabolite of vitamin D3: Haussler, et al.; PNAS 68, 177 (1971) Abstract
1,25-dihydroxycholecalciferol: a potent stimulator of bone resorption in tissue culture: Raisz, et al.; Science 175, 768 (1972) Abstract
RELATED PRODUCT GROUPS   

Natural Products / Antibiotics > Natural Products > Vitamins