Calcitriol |  | | SYNONYMS | Vitamin D3, 1α,25-Dihydroxy-
1α,25-Dihydroxyvitamin D3
1,25(OH)2D3
1α,25-Dihydroxycholecalciferol | | | | PRODUCT LINE | Bone Metabolism | | | | PRODUCT FAMILIES | Vitamin D3 & Vitamin D3 Receptor / Related Products | | | | | Product Specification | | |
| FORMULA: | C27H44O3 | | | | | |
| MW: | 416.7 | | | | | |
| CAS NUMBER: | 32222-06-3 | | | | | |
| MERCK INDEX: | 14: 1644 | | | | | |
| RTECS: | FZ4645000 | | | | | |
| PURITY: | ≥97% | | | | | |
| APPEARANCE: | White to off-white solid. | | | | | |
| SOLUBILITY: | Slightly soluble in methanol, 100% ethanol, ethyl acetate, tetrahydrofuran, DMSO, chloroform or acetone. | | | | | |
| SHIPPING: | SHIPPED ON BLUE ICE | | | | | |
| LONG TERM STORAGE: | -20°C | | | | | |
| HANDLING: | Protect from light. | | | | | |
| HAZARD: | VERY TOXIC. MAY BE TERATOGENIC. | | | | | | Product Description | Osteotropic hormone that up-regulates RANKL level and down-regulates OPG level. Biologically active form of vitamin D3 in intestinal calcium transport and bone calcium resorption. |
| | | Product Specific Literature References | A rapidly acting metabolite of vitamin D3: Haussler, et al.; PNAS 68, 177 (1971) Abstract
1,25-dihydroxycholecalciferol: a potent stimulator of bone resorption in tissue culture: Raisz, et al.; Science 175, 768 (1972) Abstract |
| | | | | RELATED PRODUCT GROUPS | Natural Products / Antibiotics > Natural Products > Vitamins | | | | | |
