Bone Morphogenetic Protein 7 (human) (recombinant) |
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| SYNONYMS | BMP-7 (human) (recombinant) |
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| PRODUCT LINE | Bone Metabolism |
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| PRODUCT FAMILIES | Bone Morphogenetic Proteins [BMPs] & Receptors / Related Products |
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| Ordering Information |
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| Product Numbers | Format | Size | Unit Price | Quantity | | | JBS-PR-408 |
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10 µg | | | | | | |
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| Product Specification |
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| MW: | ~15.68kDa. |
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| SOURCE/HOST: | Produced in E. coli. |
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| PURITY: | ≥95% (SDS-PAGE, RP-HPLC, FPLC) |
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| FORMULATION: | Lyophilized. |
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| ENDOTOXIN CONTENT: | ≤1EU/µg protein. |
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| RECONSTITUTION: | Reconstitute with double distilled sterile water (≥100µg/ml). |
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| SHIPPING: | SHIPPED ON BLUE ICE |
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| LONG TERM STORAGE: | -20°C |
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| HANDLING: | Avoid freeze/thaw cycles. |
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| Product Description |
Bone morphogenetic proteins (BMPs) are key regulators of bone formation. Bone morphogenetic protein 7 (BMP-7), a member of the TGFβ superfamily of cytokines, plays pivotal roles during embryogenic renal and eye development. In adults, BMP-7 expression is retained in only a few tissues, most prominently in kidney. In experimental rodent models of obstructive or diabetic nephropathy, exogenously administered BMP-7 reduces glomerular and tubulointerstitial fibrosis and preserves renal function. BMPs are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins. |
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| | General Information | |
Background/Technical Information | | For the Original Manufacturer’s Data Sheet please click here.
Our product description may differ slightly from the Original Manufacturer’s Data Sheet. | | |
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| RELATED PRODUCT GROUPS |
Proteins > Recombinant Proteins / Fusion Proteins |
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