Diltiazem . hydrochloride |
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| PRODUCT LINE | Signal Transduction |
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| PRODUCT FAMILIES | Ca2+ Channels (L-type) |
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| Ordering Information |
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| Product Numbers | Format | Size | Unit Price | Quantity | | | ALX-550-214-G001 |
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1 g | | | | | ALX-550-214-G005 |
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5 g | | | | | | | | Replaces Prod. #: BML-CA205 |
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| Product Specification |
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| FORMULA: | C22H26N2O4S . HCl |
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| MW: | 414.5 . 36.5 |
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| CAS NUMBER: | 33286-22-5 |
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| MERCK INDEX: | 14: 3202 |
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| RTECS: | DL0310000 |
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| PURITY: | ≥99% (HPLC) |
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| APPEARANCE: | White to off-white powder. |
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| SOLUBILITY: | Soluble in water (50mg/ml), methanol or formic acid. |
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| SHIPPING: | AMBIENT |
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| LONG TERM STORAGE: | +20°C |
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| HAZARD: | HARMFUL. |
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| Product Description |
Inhibitor of L-type Ca2+ channels. Regulates Ca2+ release from intracellular stores in neutrophils. |
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| | Product Specific Literature References | Diltiazem. A review of its pharmacological properties and therapeutic efficacy: M. Chaffman & R.N. Bogden; Drugs 29, 387 (1985) Abstract
Calcium antagonism and calcium entry blockade: T. Godfraind, et al.; Pharmacol. Rev. 38, 321 (1986) Abstract
Stereospecific action of diltiazem on the mitochondrial Na-Ca exchange system and on sarcolemmal Ca-channels: M. Chiesi, et al.; Biochem. Pharmacol. 36, 2735 (1987) Abstract |
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