Ac-IETD-CHO |
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| SYNONYMS | Caspase-8 Inhibitor (Aldehyde)
Granzyme B Inhibitor (Aldehyde) |
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| PRODUCT LINE | Cell Death / Apoptosis / Autophagy |
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| PRODUCT FAMILIES | Caspase Inhibitors |
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| Ordering Information |
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| Product Numbers | Format | Size | Unit Price | Quantity | | | ALX-260-043-M001 |
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1 mg | | | | | ALX-260-043-M005 |
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5 mg | | | | | | |
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| Product Specification |
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| SEQUENCE: | Ac-Ile-Glu-Thr-Asp-CHO |
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| FORMULA: | C21H34N4O10 |
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| MW: | 502.5 |
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| PEPTIDE CONTENT: | 70-90%. |
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| PURITY: | ≥97% (HPLC) |
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| FORMULATION: | Lyophilized. |
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| SOLUBILITY: | Soluble in DMSO. Dilute with buffer, pH 7.5. |
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| SHIPPING: | AMBIENT |
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| LONG TERM STORAGE: | -20°C |
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| USE/STABILITY: | Use always fresh solutions. |
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| HANDLING: | Keep cool and dry. |
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| Product Description |
Reversible inhibitor of caspase-8 and granzyme B. Also inhibits caspase-10. |
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| | Product Specific Literature References | | A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro: Z. Han, et al.; J. Biol. Chem. 272, 13432 (1997) Full Text; http://www.jbc.org/cgi/reprint/272/20/13432.pdf |
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| RELATED PRODUCT GROUPS |
Cell Death / Apoptosis / Autophagy > Granzymes / Related Products > Granzyme Inhibitors |
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