Ac-WEHD-CHO |
 |
| SYNONYMS | Caspase-1 Inhibitor (Aldehyde)
Caspase-5 Inhibitor (Aldehyde) |
|
|
| PRODUCT LINE | Cell Death / Apoptosis / Autophagy |
|
|
| PRODUCT FAMILIES | Caspase Inhibitors |
|
|
|
| Ordering Information |
|
| Product Numbers | Format | Size | Unit Price | Quantity | | | ALX-260-055-M001 |
|
1 mg | | | | | ALX-260-055-M005 |
|
5 mg | | | | | | |
|
|
| Product Specification |
|
|
| SEQUENCE: | Ac-Trp-Glu-His-Asp-CHO |
|
|
| |
|
| FORMULA: | C28H33N7O9 |
|
|
| |
|
| MW: | 611.6 |
|
|
| |
|
| PURITY: | ≥90% (HPLC) |
|
|
| |
|
| APPEARANCE: | White to off-white powder. |
|
|
| |
|
| FORMULATION: | TFA salt. |
|
|
| |
|
| SOLUBILITY: | Soluble in water (10mg/ml). |
|
|
| |
|
| SHIPPING: | AMBIENT |
|
|
| |
|
| LONG TERM STORAGE: | -20°C |
|
|
| |
|
| USE/STABILITY: | Solution is stable for 1 month when stored at -20°C and protected from light. |
|
|
| |
|
| HANDLING: | Keep cool and dry. |
|
|
|
|
| Product Description |
Reversible, cell permeable inhibitor of caspase-1 and -5. Also inhibits caspase-4. |
|
| | Product Specific Literature References | A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE): T.A. Rano, et al.; Chem. Biol. 4, 149 (1997) Abstract
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis: N.A. Thornberry, et al.; J. Biol. Chem. 272, 17907 (1997) Full Text; http://www.jbc.org/cgi/reprint/272/29/17907.pdf |
|
|
|
|
| RELATED PRODUCT GROUPS |
|
|
|
|
