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 ALX-260-065[ALEXIS] Revised 11-Dec-07  

Ac-LEVD-CHO

SYNONYMS   

Caspase-4 Inhibitor (Aldehyde)

PRODUCT LINE   

Cell Death / Apoptosis / Autophagy

PRODUCT FAMILIES   

Caspase Inhibitors

Ordering Information
 Product NumbersFormatSizeUnit PriceQuantity
 ALX-260-065-M001 1 mg  
 ALX-260-065-M005 5 mg  
Product Specification
SEQUENCE:   Ac-Leu-Glu-Val-Asp-CHO
 
FORMULA:   C22H36N4O9
 
MW:   500.6
 
PEPTIDE CONTENT:   70-90%.
 
PURITY:   ≥95% (HPLC)
 
APPEARANCE:   White powder.
 
FORMULATION:   Lyophilized.
 
SOLUBILITY:   Soluble in distilled water.
 
SHIPPING:   AMBIENT
 
LONG TERM STORAGE:   -20°C
 
USE/STABILITY:   Stock solutions should be divided into aliquots and stored at -20°C.
 
HANDLING:   Keep cool and dry.
Product Description

Reversible inhibitor of caspase-4. Also inhibits caspase-5.

Product Specific Literature References
A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro: R.V. Talanian, et al.; J. Biol. Chem. 272, 9677 (1997) Full Text; http://www.jbc.org/cgi/reprint/272/15/9677.pdf
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