Ac-TQTD-AFC |
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| SYNONYMS | DRONC Substrate II (Fluorogenic)
Drosophila Caspase Substrate II (Fluorogenic) |
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| PRODUCT LINE | Cell Death / Apoptosis / Autophagy |
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| PRODUCT FAMILIES | Caspase Substrates |
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| Ordering Information |
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| Product Numbers | Format | Size | Unit Price | Quantity | | | ALX-260-161-M001 |
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1 mg | | | | | ALX-260-161-M005 |
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5 mg | | | | | | |
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| Product Specification |
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| SEQUENCE: | Ac-Thr-Gln-Thr-Asp-AFC (AFC=7-Amino-4-trifluoromethylcoumarin) |
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| FORMULA: | C29H35F3N6O12 |
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| MW: | 716.6 |
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| PURITY: | ≥97% (HPLC) |
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| APPEARANCE: | Lyophilized. |
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| SOLUBILITY: | Soluble in DMSO. Dilute with buffer, pH 7.0 or higher. |
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| SHIPPING: | AMBIENT |
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| SHORT TERM STORAGE: | +4°C |
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| LONG TERM STORAGE: | -20°C |
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| HANDLING: | Packaged under inert gas. Protect from light. |
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| | Product Specific Literature References | A cloning method to identify caspases and their regulators in yeast: identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1: C.J. Hawkins, et al.; PNAS 96, 2885 (1999) Abstract
The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM: C.J. Hawkins, et al.; J. Biol. Chem. 275, 27084 (2000) Abstract |
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