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 ALX-350-156[ALEXIS] Revised 18-Feb-08  

Aerophobin-2

PRODUCT LINE   

Natural Products / Antibiotics

PRODUCT FAMILIES   

Alkaloids

Ordering Information
 Product NumbersFormatSizeUnit PriceQuantity
 ALX-350-156-M001 1 mg  
Product Specification
FORMULA:   C16H19Br2N5O4
 
MW:   505.2
 
CAS NUMBER:   87075-23-8
 
SOURCE/HOST:   Isolated from Aplysina aerophoba.
 
PURITY:   ≥97% (HPLC)
 
APPEARANCE:   White to off-white amorphous solid.
 
SOLUBILITY:   Soluble in DMSO or 100% ethanol.
 
SHIPPING:   AMBIENT
 
LONG TERM STORAGE:   -20°C
 
HANDLING:   Protect from light.
 
IDENTITY:   Identity determined by 1H-NMR.

Product Description

Cytotoxic alkaloid. Shows antibiotic properties.

Product Specific Literature References
The bromo-compounds of the true sponge Verongia aerophoba: G. Cimino, et al.; Tetrahedron Lett. 24, 3029 (1983)
Antibiotic and cytotoxic activity of brominated compounds from the marine sponge Verongia aerophoba: R. Teeyapant, et al.; Z. Naturforsch. 48, 939 (1993) Abstract
Approaches to the synthesis of some tyrosine-derived marine sponge metabolites: synthesis of verongamine and purealidin N: T.R. Boehlow, et al.; J.Org. Chem. 66, 3111 (2001) Abstract
Two unprecedented dibromotyrosine-derived alkaloids from the Brazilian endemic marine sponge Aplysina caissara: B.M. Saeki, et al.; J. Nat. Prod. 65, 796 (2002) Abstract
Chemical defense of Mediterranean sponges Aplysina cavernicola and Aplysina aerophoba: C. Thoms, et al.; Z. Naturforsch. 59, 113 (2004) Abstract
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Natural Products / Antibiotics > Natural Products > Natural Products - Anti-infective Agents > Natural Products with Antibiotic Activity / Natural Products / Antibiotics > Natural Products > Marine Natural Products