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 ALX-380-024[ALEXIS] Revised 30-Oct-07  

Actinomycin C

SYNONYMS   

Cactinomycin

PRODUCT LINE   

Natural Products / Antibiotics

PRODUCT FAMILIES   

Antitumor Antibiotics

Ordering Information
 Product NumbersFormatSizeUnit PriceQuantity
 ALX-380-024-M005 5 mg  
 ALX-380-024-M025 25 mg  
Product Specification
CAS NUMBER:   8052-16-2
 
MERCK INDEX:   14: 1606
 
SOURCE/HOST:   Isolated from Streptomyces chrysomallus.
 
PURITY:   ≥98%
 
APPEARANCE:   Orange solid.
 
FORMULATION:   Mixture of actinomycin C1(= actinomycin D) (R = R’ = D-Val)  ~3%, C2(R = D-Val, R’ = D-allo-Ile) ~45%, C3(R = R’ = D-allo-Ile) ~53%.
 
SOLUBILITY:   Soluble in methanol. Sparingly soluble in water.
 
SHIPPING:   AMBIENT
 
LONG TERM STORAGE:   +4°C
 
HANDLING:   Protect from light.
 
HAZARD:   TOXIC.

Product Description

Antibiotic complex with antitumor activity.

Product Specific Literature References
Nomenclature of the Actinomycins: S.A. Waksman, et al.; PNAS 44, 602 (1958) Abstract
General Information
For nomenclature see S.A. Waksman, E. Katz and L.C. Vining; PNAS 44, 602 (1958).
RELATED PRODUCT GROUPS   

Cancer > Antitumor Reagents > Antitumor Agents (Apoptosis Inducers) / DNA Regulation / Transcription > Transcription Inhibitors / Related Products / Natural Products / Antibiotics > Antibiotics > Antibiotics - Apoptosis Inducers & Inhibitors