Actinomycin X2 |
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| PRODUCT LINE | Natural Products / Antibiotics |
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| PRODUCT FAMILIES | Antitumor Antibiotics |
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| Ordering Information |
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| Product Numbers | Format | Size | Unit Price | Quantity | | | ALX-380-080-M001 |
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1 mg | | | | | | |
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| Product Specification |
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| FORMULA: | C62H84N12O17 |
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| MW: | 1269.4 |
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| SOURCE/HOST: | Isolated from Streptomyces sp. |
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| PURITY: | ≥95% (solvent free) |
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| APPEARANCE: | Orange crystals. |
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| SOLUBILITY: | Soluble in methanol, acetone or chloroform. |
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| SHIPPING: | AMBIENT |
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| LONG TERM STORAGE: | +4°C |
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| HANDLING: | Keep cool and dry. |
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| HAZARD: | TOXIC. |
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| IDENTITY: | Determined by 1H-NMR: Identical to standard reference. |
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| Product Description |
Antitumor antibiotic. Has higher cytotoxicity toward cultured human leukemia (HL-60) cells than actinomycin D (Prod. No. ALX-380-009). Induces cell death via apoptosis. |
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| | Product Specific Literature References | Nomenclature of the Actinomycins: S.A. Waksman, et al.; PNAS 44, 602 (1958) Abstract
Correlation of actinomycin X2 to the lipid profile in static and shaken cultures of Streptomyces nasri strain YG62: M.Y. el-Naggar, et al.; Microbios. 100, 117 (1999) Abstract
Characterization of Streptomyces MITKK-103, a newly isolated actinomycin X2-producer: K. Kurosawa, et al.; Appl. Microbiol. Biotechnol. 72, 145 (2006) Abstract |
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| RELATED PRODUCT GROUPS |
DNA Regulation / Transcription > Transcription Inhibitors / Related Products / Natural Products / Antibiotics > Antibiotics > Antibiotics - Apoptosis Inducers & Inhibitors |
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