cAMP-dependent Protein Kinase Substrate |
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| SYNONYMS | PKA Substrate |
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| PRODUCT LINE | Signal Transduction |
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| PRODUCT FAMILIES | PKA Substrates |
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| Ordering Information |
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| Product Numbers | Format | Size | Unit Price | Quantity | | | ALX-151-019-MC05 |
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0.5 mg | | | | | ALX-151-019-M001 |
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1 mg | | | | | | |
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| Product Specification |
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| SEQUENCE: | H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH |
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| FORMULA: | C92H150N28O29 |
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| MW: | 2112.4 |
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| PURITY: | ≥95% |
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| APPEARANCE: | White powder. |
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| SOLUBILITY: | Soluble in water. |
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| SHIPPING: | AMBIENT |
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| LONG TERM STORAGE: | -20°C |
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| Product Description |
Derived from the RII subunit of cAMP-dependent protein kinase (PKA). Substrate for PKA. Has been used in a non-radioactive assay of calcineurin (protein phosphatase 2B) for screening purposes. |
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| | Product Specific Literature References | Dephosphorylation of cAMP-dependent protein kinase regulatory subunit (type II) by calmodulin-dependent protein phosphatase. Determinants of substrate specificity: D.K. Blumenthal, et al.; J. Biol. Chem. 261, 8140 (1986) Full Text; http://www.jbc.org/cgi/reprint/261/18/8140.pdf
Nonradioactive assay for protein phosphatase 2B (calcineurin) activity using a partial sequence of the subunit of cAMP-dependent protein kinase as substrate: A. Enz, et al.; Anal. Biochem. 216, 147 (1994) Abstract |
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| RELATED PRODUCT GROUPS |
Peptides / Signal Transduction > Phosphatases / Related Products > Protein Serine / Threonine Phosphatases / Related Products > PP2B [Calcineurin] / Related Products |
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