Protein Synthesis, Modification & Degradation



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 ALX-430-155[ALEXIS] Revised 16-Nov-07  

4EGI-1

SYNONYMS   

α-[2-[4-(3,4-Dichlorophenyl)-2-thiazolyl]hydrazinylidene]-2-nitro-benzenepropanoic acid

PRODUCT LINE   

DNA Regulation / Transcription

PRODUCT FAMILIES   

Translation Inhibitors

Ordering Information
 Product NumbersFormatSizeUnit PriceQuantity
 ALX-430-155-M002 2 mg  
Product Specification
FORMULA:   C18H12Cl2N4O4S
 
MW:   451.3
 
CAS NUMBER:   315706-13-9
 
PURITY:   ≥95%
 
APPEARANCE:   Brown solid.
 
SOLUBILITY:   Soluble in DMSO.
 
SHIPPING:   AMBIENT
 
LONG TERM STORAGE:   -20°C
 
HANDLING:   Protect from light.
 
IDENTITY:   Determined by 1H-NMR, 13C-NMR and MS.

Product Description

Selective and cell permeable inhibitor of the interaction between the human eukaryotic translation initiation factors 4E (eIF4E) and 4G (eIF4G).

Product Specific Literature References
Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G: N.J. Moerke, et al.; Cell 128, 257 (2007) Abstract
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