N-Acetyl-eglin C (recombinant) |
 |
| PRODUCT LINE | Cancer |
|
|
| PRODUCT FAMILIES | Cathepsin Inhibitors |
|
|
|
| Ordering Information |
|
| Product Numbers | Format | Size | Unit Price | Quantity | | | ALX-201-006-MC01 |
|
0.1 mg | | | | | ALX-201-006-MC05 |
|
0.5 mg | | | | | ALX-201-006-M001 |
|
1 mg | | | | | | |
|
|
| Product Specification |
|
|
| SEQUENCE: | Ac-Thr-Glu-Phe-Gly-Ser-Glu-Leu-Lys-Ser-Phe-Pro-Glu-Val-Val-Gly-Lys-Thr-Val-Asp-Gln-Ala-Arg-Glu-Tyr-Phe-Thr-Leu-His-Tyr-Pro-Gln-Tyr-Asn-Val-Tyr-Phe-Leu-Pro-Glu-Gly-Ser-Pro-Val-Thr-Leu-Asp-Leu-Arg-Tyr-Asp-Arg-Val-Arg-Val-Phe-Tyr-Asn-Pro-Gly-Thr-Asn-Val-Val-Asn-His-Val-Pro-His-Val-Gly-OH |
|
|
| |
|
| FORMULA: | C377H552N96O107 |
|
|
| |
|
| MW: | 8141.1 |
|
|
| |
|
| CAS NUMBER: | 96380-69-7 |
|
|
| |
|
| SOURCE/HOST: | Produced in E. coli. |
|
|
| |
|
| PURITY: | ≥97% (HPLC) |
|
|
| |
|
| APPEARANCE: | White to off-white powder. |
|
|
| |
|
| SOLUBILITY: | Soluble in water. |
|
|
| |
|
| SHIPPING: | SHIPPED ON BLUE ICE |
|
|
| |
|
| LONG TERM STORAGE: | -20°C |
|
|
|
|
| Product Description |
Eglin C was originally isolated from the leech Hirudo medicinalis [1]. Recombinant N-acetyl-eglin C is a 70 amino acid peptide with identical biological activity to native eglin C. An effective inhibitor of chymotrypsin and subtilisin as well as of leukocyte elastase and cathepsin G. |
|
| | Product Specific Literature References | [1] Structure of the elastase-cathepsin G inhibitor of the leech Hirudo medicinalis: U. Seemüller, et al.; Hoppe-Seyler's Z. Physiol. Chem. 361, 1841 (1980) Abstract
[2] A large fragment approach to DNA synthesis: total synthesis of a gene for the protease inhibitor eglin c from the leech Hirudo medicinalis and its expression in E. coli: H. Rink, et al.; Nucl. Acids Res. 12, 6369 (1984) Abstract |
|
| | General Information | |
Background/Technical Information | | Swiss-Prot link P01051: Eglin C (Hirudo medicinalis) | | |
|
|
|
| RELATED PRODUCT GROUPS |
Proteins > Recombinant Proteins / Fusion Proteins / Signal Transduction > Signal Transduction Enzymes / Related Products > Proteases / Related Products > Proteases Other Products |
|
|
|
