ACRP30headless (human) (recombinant) |
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| SYNONYMS | Tail Adiponectin (human) (recombinant)
Tail-Adp (human) (recombinant)
Adipocyte Complement Related Protein of 30kDa headless (human) (recombinant) |
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| PRODUCT LINE | Obesity & Adipokines |
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| PRODUCT FAMILIES | Adiponectin [ACRP30] / Related Products |
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| Ordering Information |
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| Product Numbers | Format | Size | Unit Price | Quantity | | | ALX-203-002-C010 |
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10 µg | | | | | | |
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| Product Specification |
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| MW: | ~27kDa (SDS-PAGE). |
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| SOURCE/HOST: | Produced in HEK 293 cells. The non-homologous (aa 16-45) and collagen domain of human ACRP30 (aa 45-108) are fused at the N-terminus to a FLAG®-tag. |
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| CONCENTRATION: | 0.1mg/ml after reconstitution. |
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| PURITY: | ≥95% (SDS-PAGE) |
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| FORMULATION: | Lyophilized. Contains PBS. |
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| ENDOTOXIN CONTENT: | <0.1EU/µg purified protein (LAL test; Bio Whittaker). |
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| RECONSTITUTION: | Reconstitute with 100µl sterile water. |
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| APPLICATION: | Negative control. When used at 1µg/g body weight in mouse demonstrated no significant bioactivity in terms of reduction of serum glucose compared to wildtype in an in vivo assay. Control compound for rhsMegaAPRIL™ (Prod. No. ALX-522-035) and rhsMegaTNF-α (Prod. No. ALX-522-046). |
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| SHIPPING: | SHIPPED ON BLUE ICE |
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| LONG TERM STORAGE: | -20°C |
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| USE/STABILITY: | Stable for at least 6 months after receipt when stored as recommended. |
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| HANDLING: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C. |
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| | Product Specific Literature References | Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin: Implications for metabolic regulation and bioactivity: U.B. Pajvani, et al.; J. Biol. Chem. 278, 9073 (2003) Full Text; http://www.jbc.org/cgi/reprint/M207198200v1.pdf
Adiponectin acts in the brain to decrease body weight: Y. Qi, et al.; Nat. Med. 10, 524 (2004) Abstract |
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| RELATED PRODUCT GROUPS |
Proteins > Recombinant Proteins / Fusion Proteins |
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